SIMPLIFYING COMPLEXITY:
BIOREACTOR INFLATION
Challenge
Single Use bioreactors consist of a pre-sterilised, disposable plastic bag as the culture vessel, housed within permanent hardware. Used in the early production of medicines, they eliminate the need for cleaning and sterilisation between batches. However, they are incredibly challenging and time-consuming to install and inflate as they consist of a hugely complex array of parts that need to remain sterile and avoid damage which would compromise the viability, quality, and result in potential production loss.
Solution
We created a single use bioreactor configured into a unique packaging design solution. This provides protection during transport, simpler handling, and a cartridge concept combined with an inflation mechanism that enables groundbreakingly fast installation and inflation of less than 30 minutes.
Manufacturing Processes
Multiple and varied as expected from highly complex system
Materials
Multiple and varied
Patents
- EP 3 081 286 A1
- US 9,687,852 B2
- US 9,714,405 B2
- US 2016/0303567 A1
- US 9,714,405 B2
Company
Company: Pall/Cytiva
BIOREACTOR INFLATION
"Simplifying complexity"
Challenge
Single Use bioreactors consist of a pre-sterilised, disposable plastic bag as the culture vessel, housed within permanent hardware. Used in the early production of medicines, they eliminate the need for cleaning and sterilisation between batches. However, they are incredibly challenging and time-consuming to install and inflate as they consist of a hugely complex array of parts that need to remain sterile and avoid damage which would compromise the viability, quality, and result in potential production loss.
Solution
We created a single use bioreactor configured into a unique packaging design solution. This provides protection during transport, simpler handling, and a cartridge concept combined with an inflation mechanism that enables groundbreakingly fast installation and inflation of less than 30 minutes.
Manufacturing Processes
Multiple and varied as expected from highly complex system
Materials
Multiple and varied
Patents
- EP 3 081 286 A1
- US 9,687,852 B2
- US 9,714,405 B2
- US 2016/0303567 A1
- US 9,714,405 B2
Company
Company: Pall/Cytiva
